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KMID : 1143420180110351152
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Public Health Weekly Report
2018 Volume.11 No. 35 p.1152 ~ p.1162
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The Korean Stroke Cohort for Functioning and Rehabilitation (KOSCO)
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Kang Sung-Hyun
Choi Yong-Joo
Lee Kang-Hee
Kim Yun-Hee
Chang Won-Hyuk
Shin Min-A
Kim Deog-Young
Lee Jong-Min
Sohn Min-Kyun
Lee Sam-Gyu
Kim Soo-Yeon
Shin Yong-Il
Lee Yang-Soo
Joo Min-Cheol
Oh Gyung-Jae
Lee Young-Hoon
Han Eun-Young
Han Jun-Hee
Ahn Jeong-Hoon
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Abstract
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Background: The incidence of stroke has increased, and stroke survivors are left with variable degree of residual
disabilities, which confers a significant burden on patients, caregivers, and the society. Development of structured stroke
care requires long-term assessment of functional outcomes to identify the factors influencing residual disability and quality
of life in stroke survivors.
Methods: The Korean Stroke Cohort for Functioning and Rehabilitation (KOSCO) is a prospective, multi-center, longitudinal
follow-up study for investigating the survival and recurrence rates, functional status, mood, and quality of life in patients
with ischemic or hemorrhagic first-ever stroke based on face-to-face assessments and interviews. We also conducted
rehabilitation intervention studies to investigate the effects of early intensive rehabilitation therapies on long-term
functional outcomes.
Results: Of 10,636 patients with first-ever stroke who were admitted to 9 hospitals nationwide, 7,858 patients who agreed
to participate in the follow-up study were enrolled. This study maintained a follow-up rate higher than 70%, and it is
currently conducting the 7th year of the 10-year planned study duration. By analyzing the follow-up dataset, the risk of
mortality and recurrent vascular events were determined. The residual functional disabilities, health status, mood, and
quality of life in stroke survivors were delineated as well. Factors influencing the residual disability and long-term quality of
life in stroke survivors were also identified. In addition, we analyzed the cost-effectiveness of early intensive rehabilitation
therapy in reducing residual disability after first-ever stroke.
Conclusion: These results provide useful information for establishing a comprehensive and structured stroke care system
and developing national policy on stroke management.
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KEYWORD
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Stroke, Incidence, Quality of life, Prospective studies, Follow-up studies
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